BCRMU provides expert advice on various aspects of biostatistics and clinical research methodology to support research activities, including but not limited to grant application and manuscript preparation.

BCRMU can provide help on
• Study design – Parallel design, crossover design, adaptive design, withdrawal design, sequential design Questionnaire design – Quantitative and/or qualitative questions related to research interest. Keep your questions focused. Data collection methods by mail, telephone, online, or in-person.
• Database design – Design case report form (CRF) or eCRF to collect high-quality study data.
• Sample size estimation – Sample size using 80% power, 90% power. If not enough power, estimate confidence interval based on feasible number of subjects.
• Randomization strategy – Open label, single blind, double blind
• Statistical analysis plan – Statistical method to analyze each study outcome, for example two-sample t-test, logistic regression, survival analysis, categorial analysis, etc.
• Data interpretation – Review analysis results, draw study conclusion, subgroup analysis results discussion/suggestions.

BCRMU can also help to address reviewer’s comments on statistical analysis methods and data analysis results, serve as a key member on Data Monitoring Committee and Safety Review Committee or even present on grant workshops or research forums.

All staff and postgraduate students of HKU LKS Faculty of Medicine.

Technical support and consultancy service for grant applications are provided free of charge to HKUMed Researchers (Fees are covered by LKS Faculty of Medicine).

As soon as you have a valid research idea and have done some literature search to understand the research gap, please contact BCRMU.

No. You don’t need to have a complete draft proposal before you schedule a meeting with us. As long as you have some clear ideas on your research objectives, have done some literature review and can confirm there are some research gaps. BCRMU will review the background information with you and suggest next steps.

The primary outcome you are interested, the null hypothesis you plan to test in the study, historical data/pilot data on the primary outcome or similar outcomes.

It normally takes about two weeks for BCRMU to review background information, historical studies and exchange ideas to decide the overall picture of a study proposal.

Please contact us through our website (https://bcrmu.sph.hku.hk/) or by email to hzhi@hku.hk to arrange a meeting.